Industry

Biotechnology stocks

200 Biotechnology companies have a page on Investingly, worth $1.07T together. The largest is Vertex Pharmaceuticals (VRTX) at $123.0B.

The median company trades at 17.1 times earnings, keeps -33.2% of revenue as operating profit and grew revenue 16.4% over the last year.

Nuvation Bio grew revenue fastest (+556%); Arbutus Biopharma has the widest operating margin (82%); 3 of them pay a dividend (median yield 0.5%).

Companies200
Total market cap$1.07T
Median P/E17.1x
Median operating margin-33.2%
Median revenue growth+16.4%
Median dividend yield0.5%

Biotechnology companies, largest first

#CompanyMarket capP/EP/FCFRevenue growthOperating marginROEDividend yield
1 Vertex Pharmaceuticals IncVRTX $123.0B28.8x38.5x+12.4%38.0%21.8%—
2 Moderna IncMRNA $81.0B——+2.1%-149.0%-46.6%—
3 Regeneron Pharmaceuticals IncREGN $68.5B16.0x16.8x+16.7%24.7%13.7%0.56%
4 argenx NV ADRARGX $50.6B42.2x60.0x+88.6%24.8%43.5%—
5 Revolution Medicines IncRVMD $39.6B——-100.0%—-67.8%—
6 BeiGene, Ltd.ONC $34.1B74.1x36.2x+29.6%15.1%12.7%—
7 Royalty Pharma PlcRPRX $32.3B29.5x13.0x+16.5%59.6%8.3%—
8 Alnylam Pharmaceuticals IncALNY $30.6B57.4x65.7x+66.9%—54.1%—
9 Roivant Sciences LtdROIV $27.2B——-33.5%-7914.8%-6.3%—
10 BioNTech SEBNTX $24.5B——+4.3%-49.0%-5.9%—
11 Genmab ASGMAB $22.0B27.2x19.1x+30.7%31.1%25.3%—
12 Incyte CorporationINCY $21.8B15.4x16.1x+20.9%30.1%25.5%—
13 Insmed IncINSM $19.6B——+296.1%-73.9%-115.5%—
14 Exelixis IncEXEL $14.3B18.8x16.9x+10.6%39.9%46.7%—
15 Ascendis Pharma ASASND $13.8B25.3x317.1x+42.3%-18.9%——
16 Corcept Therapeutics IncorporatedCORT $12.8B342.0x90.6x+31.7%0.77%7.8%—
17 Halozyme Therapeutics IncHALO $12.6B37.1x19.5x+47.7%35.9%288.1%—
18 BridgeBio Pharma IncBBIO $12.3B——+120.4%-69.8%——
19 Summit Therapeutics PLCSMMT $12.1B————-135.9%—
20 Bio-Techne CorpTECH $11.5B104.9x44.8x+1.3%20.7%8.6%0.43%
21 Madrigal Pharmaceuticals IncMDGL $10.7B——+71.2%-25.1%-62.1%—
22 Immunitybio IncIBRX $10.5B——+93.9%-151.9%——
23 Biomarin Pharmaceutical IncBMRN $10.2B38.1x14.1x+19.9%4.4%1.1%—
24 Krystal Biotech IncKRYS $9.3B42.4x49.3x+24.1%44.9%17.8%—
25 Vaxcyte IncPCVX $9.0B————-38.6%—
26 Caris Life Sciences, Inc. Common StockCAI $8.9B—132.9x+45.4%15.5%17.8%—
27 Protagonist Therapeutics IncPTGX $8.8B—156.1x+3749.2%20.7%9.8%—
28 Kymera Therapeutics IncKYMR $8.7B——+466.4%-333.5%-19.9%—
29 Arrowhead Pharmaceuticals IncARWR $8.7B39.3x55.5x+171.0%-33.8%-68.7%—
30 Axsome Therapeutics IncAXSM $8.4B——+45.5%-24.0%-230.1%—
31 Cytokinetics IncCYTK $8.4B——-57.1%-1046.1%——
32 TG Therapeutics IncTGTX $7.5B17.1x—+70.3%17.1%73.1%—
33 Spyre Therapeutics Inc.SYRE $7.2B————-16.2%—
34 Ionis Pharmaceuticals IncIONS $7.1B——-40.7%-68.0%-128.5%—
35 Praxis Precision Medicines IncPRAX $6.7B——-100.0%—-25.3%—
36 Abivax SA American Depositary SharesABVX $6.6B——-89.8%-5384.2%-73.8%—
37 Iovance Biotherapeutics IncIOVA $6.4B——+65.7%-92.7%-39.3%—
38 Ligand Pharmaceuticals IncorporatedLGND $6.1B39.5x124.2x+33.7%32.6%20.4%—
39 Rhythm Pharmaceuticals IncRYTM $5.9B——+46.9%-83.6%-199.4%—
40 Belite Bio Inc ADRBLTE $5.8B————-10.1%—
41 Immunovant IncIMVT $5.6B————-73.2%—
42 Kodiak Sciences IncKOD $5.4B————-396.1%—
43 Erasca IncERAS $5.3B————-79.4%—
44 PTC Therapeutics IncPTCT $5.1B6.69x7.31x+101.5%12.4%——
45 CG Oncology, Inc. Common stockCGON $5.1B———-4056.2%-21.8%—
46 Cogent Biosciences IncCOGT $5.0B——-100.0%—-70.8%—
47 Crispr Therapeutics AGCRSP $4.8B——+1041.4%-3990.0%-25.8%—
48 Scholar Rock Holding CorpSRRK $4.8B————-161.0%—
49 Mirum Pharmaceuticals IncMIRM $4.7B—84.9x+37.9%-134.9%——
50 Oruka Therapeutics, Inc.ORKA $4.6B————-11.9%—
51 Travere Therapeutics IncTVTX $4.6B—121.7x+48.2%-6.8%-177.2%—
52 Dianthus Therapeutics Inc.DNTH $4.5B——-78.6%—-16.4%—
53 Edgewise Therapeutics IncEWTX $3.9B————-44.0%—
54 Definium Therapeutics, Inc.DFTX $3.8B————-38.5%—
55 Telix Pharmaceuticals LimitedTLX $3.7B——+55.6%3.7%-1.7%—
56 Celcuity LLCCELC $3.5B——————
57 Xenon Pharmaceuticals IncXENE $3.4B————-32.9%—
58 Relay Therapeutics IncRLAY $3.4B——-48.3%-2999.4%-32.1%—
59 Arcutis Biotherapeutics IncARQT $3.3B——+59.3%7.4%12.9%—
60 ACADIA Pharmaceuticals IncACAD $3.3B8.64x31.1x+16.4%7.6%29.1%—
61 Ideaya Biosciences IncIDYA $3.3B———-92.7%-14.6%—
62 Legend Biotech CorpLEGN $3.2B——+421.9%—-29.6%—
63 Viking Therapeutics IncVKTX $3.2B————-131.0%—
64 Tarsus Pharmaceuticals IncTARS $3.0B——+69.4%-8.0%-13.4%—
65 Arcus Biosciences IncRCUS $2.9B——-74.4%-415.4%-99.1%—
66 Precigen IncPGEN $2.8B——+6322.7%—-361.9%—
67 Tango Therapeutics IncTNGX $2.6B——-100.0%-253.4%-12.1%—
68 Dyne Therapeutics IncDYN $2.6B————-74.0%—
69 Zai Lab LtdZLAB $2.6B——-3.1%-59.5%-31.0%—
70 Enliven Therapeutics Inc.ELVN $2.4B————-11.8%—
71 NewAmsterdam Pharma Company N.V. Ordinary SharesNAMS $2.4B——-80.7%-3432.2%-41.1%—
72 Harmony Biosciences HoldingsHRMY $2.4B16.5x6.82x+30.3%24.0%18.1%—
73 ADMA Biologics IncADMA $2.4B15.0x85.1x+2.0%43.8%41.4%—
74 Nurix Therapeutics IncNRIX $2.3B——-79.5%-982.4%-84.8%—
75 Beam Therapeutics IncBEAM $2.3B——-94.2%-242.3%-8.0%—
76 Celldex Therapeutics IncCLDX $2.3B——-97.0%-206220.2%-42.1%—
77 Disc Medicine Inc.IRON $2.3B————-38.2%—
78 MBX Biosciences, Inc. Common StockMBX $2.2B————-25.5%—
79 Recursion Pharmaceuticals IncRXRX $2.2B——-60.1%-991.7%-56.7%—
80 Vericel Corp OrdVCEL $2.2B97.9x86.9x+22.5%6.0%6.5%—
81 Immunome IncIMNM $2.1B——-100.0%—-48.4%—
82 Novavax IncNVAX $2.1B4.30x—-76.3%-56.6%——
83 Viridian Therapeutics IncVRDN $2.1B——+278.7%-569.7%-58.5%—
84 Aurinia Pharmaceuticals IncAUPH $2.1B7.27x15.4x+18.9%48.4%51.1%—
85 Mineralys Therapeutics, Inc. Common StockMLYS $2.0B————-63.5%—
86 Pharvaris BVPHVS $2.0B————-95.3%—
87 Septerna, Inc. Common StockSEPN $2.0B—17.8x+22375.6%-44.0%-6.3%—
88 Zymeworks Inc. Common StockZYME $1.9B——-90.6%-419.0%-186.6%—
89 Palvella Therapeutics, IncPVLA $1.9B——-100.0%—-28.4%—
90 Vera Therapeutics IncVERA $1.9B————-98.6%—
91 Lakefront Biotherapeutics NVLKFT $1.9B3.29x—+303.5%26.5%12.1%—
92 Fortrea Holdings Inc.FTRE $1.9B—21.1x-4.5%-0.40%-16.2%—
93 Agios PharmAGIO $1.9B——+259.2%-466.8%-40.1%—
94 Vir Biotechnology IncVIR $1.8B——+19582.5%-92.4%-25.6%—
95 Mesoblast LtdMESO $1.8B——+191.4%—-20.4%—
96 Biohaven Pharmaceutical Holding Co LtdBHVN $1.8B————-4801.5%—
97 Structure Therapeutics Inc. American Depositary SharesGPCR $1.7B————-15.9%—
98 Trevi Therapeutics IncTRVI $1.7B————-15.9%—
99 UroGen Pharma LtdURGN $1.7B——+199.2%-35.3%——
100 Sarepta Therapeutics IncSRPT $1.7B——-35.9%-10.2%-8.9%—
101 Zenas BioPharma, Inc. Common StockZBIO $1.7B————-196.0%—
102 Intellia Therapeutics IncNTLA $1.6B——-46.2%-711.7%-55.0%—
103 Nuvation Bio IncNUVB $1.6B——+555.6%-81.0%-59.0%—
104 Absci CorpABSI $1.5B——-46.4%-8084.5%-49.2%—
105 Innoviva IncINVA $1.5B3.26x7.68x+19.2%37.0%29.0%—
106 Immunocore Holdings LtdIMCR $1.5B——+18.3%-5.2%-4.3%—
107 Stoke Therapeutics IncSTOK $1.5B—32.8x-32.5%-809.7%-60.2%—
108 GH Research PLCGHRS $1.5B————-17.2%—
109 Syndax Pharmaceuticals IncSNDX $1.5B——+91.8%-77.0%-1462.1%—
110 Ocular Therapeutix IncOCUL $1.4B——+0.1%-603.0%-58.0%—
111 Rapport Therapeutics, Inc. Common StockRAPP $1.4B————-32.4%—
112 UltragenyxRARE $1.4B——+28.1%-73.6%——
113 Alpha Tau Medical LtdDRTS $1.3B————-55.3%—
114 Inhibrx Biosciences, Inc.INBX $1.3B——-100.0%———
115 Damora Therapeutics, Inc.DMRA $1.3B————-50.9%—
116 AnaptysBio IncANAB $1.3B—65.7x+23.5%131.7%1849.1%—
117 Ascentage Pharma Group InternationalAAPG $1.3B——+341.8%—-153.5%—
118 Nektar TherapeuticsNKTR $1.2B——-9.3%-257.8%-17.4%—
119 Omeros CorporationOMER $1.2B15.0x—————
120 Oric Pharmaceuticals IncORIC $1.2B————-36.8%—
121 Uniqure NVQURE $1.2B——+127.3%-1059.7%-139.9%—
122 Tyra Biosciences IncTYRA $1.1B————-42.0%—
123 Bicara Therapeutics Inc. Common StockBCAX $1.1B————-39.5%—
124 Taysha Gene Therapies IncTSHA $1.1B——-100.0%-2792.3%-38.6%—
125 Immatics NVIMTX $1.1B————-42.3%—
126 Adlai Nortye Ltd. American Depositary SharesANL $975M————-203.5%—
127 NanobiotixNBTX $952M———-33.2%——
128 Savara IncSVRA $922M——-100.0%—-97.0%—
129 Cullinan Oncology LLCCGEM $891M————-63.6%—
130 Arbutus Biopharma CorpABUS $866M5.28x—-90.6%82.0%59.2%—
131 Alto Neuroscience, Inc.ANRO $860M————-38.4%—
132 Monte Rosa Therapeutics IncGLUE $858M——-61.3%-633.0%-33.1%—
133 Alumis IncALMS $840M——-37.7%-6204.4%-97.1%—
134 Ardelyx IncARDX $791M——+23.8%-7.9%-37.4%—
135 Ginkgo Bioworks HoldingsDNA $762M——-48.5%-259.9%-69.2%—
136 ArriVent BioPharma, Inc. Common StockAVBP $751M————-44.6%—
137 MoonLake ImmunotherapeuticsMLTX $738M————-61.6%—
138 Candel Therapeutics IncCADL $714M——+0.0%—-70.2%—
139 Olema Pharmaceuticals IncOLMA $702M————-47.5%—
140 Corvus Pharmaceuticals IncCRVS $696M————-24.0%—
141 Aura Biosciences IncAURA $696M————-41.6%—
142 Pharming Group NVPHAR $674M—13.7x+26.6%6.9%1.0%—
143 Design Therapeutics IncDSGN $669M————-35.1%—
144 Jade Biosciences, Inc.JBIO $661M————-34.8%—
145 Avalo Therapeutics IncAVTX $641M——-69.3%—-22.4%—
146 Annexon IncANNX $630M————-108.9%—
147 Inventiva SaIVA $613M——-47.4%-1060.6%——
148 Achieve Life Sciences IncACHV $611M——————
149 4D Molecular Therapeutics IncFDMT $610M——+25106.7%-214.2%-44.0%—
150 Wave Life Sciences LtdWVE $585M——-73.9%—-44.6%—
151 CorMedix IncCRMD $583M3.42x3.38x+156.5%47.0%40.6%—
152 DBV TechnologiesDBVT $581M——-53.3%-3543.1%-109.7%—
153 Climb Bio IncCLYM $580M————-24.1%—
154 Fennec Pharmaceuticals IncFENC $524M——+85.2%-1.9%-7.7%—
155 CytomX Therapeutics IncCTMX $522M——-92.4%-476.2%-26.4%—
156 Contineum Therapeutics, Inc. Class A Common StockCTNM $485M————-24.0%—
157 Aclaris Therapeutics IncACRS $474M——-8.3%-1050.2%-60.8%—
158 Altimmune IncALT $471M——+420.0%—-19.4%—
159 Autolus Therapeutics LtdAUTL $459M——+118.4%-210.8%-374.4%—
160 Arvinas IncARVN $453M——+1014.7%-5.7%1.6%—
161 Oculis Holding AG Ordinary sharesOCS $448M——+74.8%-6811.7%-69.2%—
162 DiaMedica Therapeutics IncDMAC $435M————-97.9%—
163 Allogene Therapeutics IncALLO $432M————-37.9%—
164 Capricor Therapeutics IncCAPR $430M——-7.9%—-52.6%—
165 Crescent Biopharma, Inc.CBIO $419M————-58.8%—
166 Atea Pharmaceuticals IncAVIR $370M————-81.0%—
167 Arcturus Therapeutics Holdings IncARCT $353M——-89.5%-348.3%-54.3%—
168 Agenus IncAGEN $330M3.86x—+34.4%27.3%——
169 Assembly Biosciences IncASMB $327M257.0x—+38.9%—-0.01%—
170 Artiva Biotherapeutics, Inc. Common StockARTV $314M——-100.0%—-26.1%—
171 C4 Therapeutics IncCCCC $314M——+2.8%-319.0%-41.0%—
172 Benitec Biopharma Ltd ADRBNTC $295M————-25.7%—
173 Cabaletta Bio IncCABA $290M————-86.1%—
174 BridgeBio Oncology Therapeutics, Inc.BBOT $279M————-56.4%—
175 Eyepoint Pharmaceuticals IncEYPT $265M——-90.5%-11365.2%-184.3%—
176 Abeona Therapeutics IncABEO $265M4.89x—+2745.0%-327.6%-49.1%—
177 Bicycle Therapeutics LtdBCYC $255M——-78.5%-343.6%-37.3%—
178 AC Immune LtdACIU $253M——-86.9%-1940.0%-94.2%—
179 Alector IncALEC $232M——-57.8%-912.4%——
180 InflaRx N.V.IFRX $229M——-82.3%—-80.0%—
181 ADC Therapeutics SAADCT $205M——+3.0%-128.5%——
182 Alpha Cognition IncACOG $199M——+267.6%-190.6%-44.3%—
183 CompugenCGEN $191M5.61x6.10x+161.1%43.0%34.4%—
184 CAMP4 THERAPEUTICS CORPORATIONCAMP $187M——+18.8%———
185 AN2 Therapeutics IncANTX $175M————-47.8%—
186 Compass Therapeutics Inc.CMPX $173M————-44.2%—
187 Adagene IncADAG $173M——+7332.8%-279.5%-49.8%—
188 Alx Oncology Holdings ALXO $168M——-100.0%—-59.4%—
189 Precision BioSciences IncDTIL $151M——-100.0%-80.8%-116.4%—
190 Canton Strategic Holdings, Inc.CNTN $143M————-21.6%—
191 Acumen Pharmaceuticals IncABOS $142M————-183.4%—
192 Anavex Life Sciences CorpAVXL $130M————-11.6%—
193 Coya Therapeutics, Inc. Common StockCOYA $127M——+49.0%-288.7%-50.1%—
194 Codexis IncCDXS $126M——-2.7%-35.6%-93.2%—
195 Cellectis SACLLS $125M——+75.8%-45.3%-69.6%—
196 Armata Pharmaceuticals IncARMP $122M——————
197 Cibus Global LLCCBUS $113M——+6.5%-1450.6%-663.4%—
198 Foghorn Therapeutics IncFHTX $107M——+112.7%-198.0%——
199 Fortress Biotech Inc Pref Series AFBIOP $102M——+18.9%-43.9%68.1%—
200 Black Diamond Therapeutics IncBDTX $101M4.43x3.40x——-44.3%—

Medians use companies with a value for that measure; P/E only counts companies with positive earnings. Every company links to its page with the reverse DCF, insider buying and 13F holders.

Other Healthcare industries

Drug Manufacturers - General17 companiesDiagnostics & Research28 companiesMedical Devices43 companiesHealthcare Plans10 companiesMedical Instruments & Supplies25 companiesDrug Manufacturers - Specialty & Generic40 companiesMedical Distribution5 companiesMedical Care Facilities29 companiesHealth Information Services17 companies

Questions

What are the largest Biotechnology stocks?

By market value: Vertex Pharmaceuticals (VRTX), Moderna (MRNA), Regeneron Pharmaceuticals (REGN), argenx NV ADR (ARGX), Revolution Medicines (RVMD).

What is the average P/E ratio of Biotechnology stocks?

The median Biotechnology company on Investingly trades at 17.1 times trailing earnings (companies with positive earnings only).

How many Biotechnology stocks pay a dividend?

3 of 200, with a median yield of 0.5%.

Prices and ratios as of Oct 11, 2026. Statements from SEC filings. Information only, not investment advice.