Twist Bioscience (TWST)

Healthcare · Diagnostics & Research
$166.97 -18.55% on the day Market cap $10.3B 52-week range $23.30 to $219.71 Prices as of Oct 7, 2026

What the price implies

A reverse DCF: instead of guessing a fair value, it asks what growth today's price already assumes. How it works.

Twist Bioscience's free cash flow was negative in fiscal 2025, so a cash-flow reverse DCF doesn't give a meaningful answer. The Modeling tab works from revenue and margins instead.

Fundamental grade

F

Five factors scored 1 to 9 from TWST's latest numbers, weighted into one grade. It describes the business, not whether the stock is a buy.

Valuation1
Profitability0
Growth4
Financial health6
Cash efficiency0

Key numbers

P/E (trailing)—
P/E (forward)0.00x
Price / free cash flow—
EV / EBITDA—
Price / sales23.8x
Price / book20.8x
Revenue growth+23.2%
Operating margin-33.6%
Net margin-31.7%
Return on equity-30.7%
Dividend yield—
Debt / equity0.51x

Results from SEC filings

Fiscal years, from Twist Bioscience's 10-K filings. The deep dive has 15+ years, quarters and every line.

Fiscal year20212022202320242025
Revenue$132M$204M$245M$313M$377M
Net income-$152M-$218M-$205M-$209M-$78M
Free cash flow-$139M-$226M-$170M-$69M-$76M
EPS (diluted)-$3.15-$4.04-$3.60-$3.60-$1.30
Operating margin-115.4%-115.3%-88.6%-70.6%-36.2%

Where the revenue comes from

Revenue by products, fiscal 2025.

NGS tools$208M55%
Synthetic genes$114M30%
Antibody discovery$23M6%
Oligo pools$20M5%
DNA libraries$11M3%

Superinvestors who own TWST

From each investor's latest 13F filing (what a 13F shows). 3 of the investors we track hold it.

InvestorLast quarterValue% of portfolioQuarter
Tom Steyer
Farallon Capital Management LLC
Added $220M1.0%Q2 2026
Cliff Asness
AQR Capital Management
Added $13M0.00%Q2 2026
Joel Greenblatt
Gotham Asset Management
New position $326,0270.00%Q2 2026

Insider buying

Open-market purchases by Twist Bioscience's executives and directors in the last 12 months, from SEC Form 4 filings. What insider buying tells you.

No open-market insider purchases of TWST in the last 12 months. Most insider activity is selling and option exercises, which aren't shown here.

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In the full deep dive

DCF fair value per share
Yearly return (IRR) at today's price
Growth implied by revenue and margins
15+ years of statements and quarters

Questions

Are Twist Bioscience insiders buying the stock?

No open-market insider purchases of TWST in the last 12 months, according to SEC Form 4 filings.

Which superinvestors own Twist Bioscience?

3 of the superinvestors Investingly tracks hold TWST in their latest 13F, including Tom Steyer, Cliff Asness, Joel Greenblatt.

Prices and ratios as of Oct 7, 2026; statements from SEC filings. Information only, not investment advice. Superinvestor holdings come from 13F filings, which are filed up to 45 days after each quarter ends.