Axsome Therapeutics (AXSM)

Healthcare · Biotechnology
$173.60 -0.42% on the day Market cap $8.7B 52-week range $117.30 to $260.19 Prices as of Oct 7, 2026

What the price implies

A reverse DCF: instead of guessing a fair value, it asks what growth today's price already assumes. How it works.

Axsome Therapeutics's free cash flow was negative in fiscal 2025, so a cash-flow reverse DCF doesn't give a meaningful answer. The Modeling tab works from revenue and margins instead.

Fundamental grade

F

Five factors scored 1 to 9 from AXSM's latest numbers, weighted into one grade. It describes the business, not whether the stock is a buy.

Valuation2
Profitability0
Growth9
Financial health2
Cash efficiency0

Key numbers

P/E (trailing)—
P/E (forward)245.9x
Price / free cash flow—
EV / EBITDA—
Price / sales11.2x
Price / book151.1x
Revenue growth+45.5%
Operating margin-24.0%
Net margin-24.7%
Return on equity-230.1%
Dividend yield—
Debt / equity8.14x

Results from SEC filings

Fiscal years, from Axsome Therapeutics's 10-K filings. The deep dive has 15+ years, quarters and every line.

Fiscal year20212022202320242025
Revenue—$50M$271M$386M$638M
Net income-$130M-$187M-$239M-$287M-$183M
Free cash flow-$109M-$117M-$146M-$129M-$94M
EPS (diluted)-$3.47-$4.60-$5.27-$5.99-$3.68
Operating margin—-359.3%-85.7%-72.7%-26.1%

Where the revenue comes from

Revenue by products, fiscal 2025.

Product Sales$634M99%
Royalty and Milestone Revenue$5M1%

Superinvestors who own AXSM

From each investor's latest 13F filing (what a 13F shows). 4 of the investors we track hold it.

InvestorLast quarterValue% of portfolioQuarter
Hersh Cohen
ClearBridge Investments
Added $60M0.05%Q2 2026
Cliff Asness
AQR Capital Management
Added $28M0.01%Q2 2026
Ron Baron
Baron Capital (BAMCO)
New position $734,3100.00%Q2 2026
Joel Greenblatt
Gotham Asset Management
New position $239,8750.00%Q2 2026

Insider buying

Open-market purchases by Axsome Therapeutics's executives and directors in the last 12 months, from SEC Form 4 filings. What insider buying tells you.

No open-market insider purchases of AXSM in the last 12 months. Most insider activity is selling and option exercises, which aren't shown here.

Get an alert at your buy price

Pick the price you'd be interested at. We'll email you when AXSM trades at or below it.

$

Free accounts get 3 price alerts. No card needed.

In the full deep dive

DCF fair value per share
Yearly return (IRR) at today's price
Growth implied by revenue and margins
15+ years of statements and quarters

Questions

Are Axsome Therapeutics insiders buying the stock?

No open-market insider purchases of AXSM in the last 12 months, according to SEC Form 4 filings.

Which superinvestors own Axsome Therapeutics?

4 of the superinvestors Investingly tracks hold AXSM in their latest 13F, including Hersh Cohen, Cliff Asness, Ron Baron.

Prices and ratios as of Oct 7, 2026; statements from SEC filings. Information only, not investment advice. Superinvestor holdings come from 13F filings, which are filed up to 45 days after each quarter ends.