Iovance Biotherapeutics (IOVA)

Healthcare · Biotechnology
$12.96 -8.41% on the day Market cap $5.7B 52-week range $1.66 to $15.30 Prices as of Oct 7, 2026

What the price implies

A reverse DCF: instead of guessing a fair value, it asks what growth today's price already assumes. How it works.

Iovance Biotherapeutics's free cash flow was negative in fiscal 2025, so a cash-flow reverse DCF doesn't give a meaningful answer. The Modeling tab works from revenue and margins instead.

Fundamental grade

D

Five factors scored 1 to 9 from IOVA's latest numbers, weighted into one grade. It describes the business, not whether the stock is a buy.

Valuation2
Profitability0
Growth9
Financial health8
Cash efficiency0

Key numbers

P/E (trailing)—
P/E (forward)0.00x
Price / free cash flow—
EV / EBITDA—
Price / sales17.6x
Price / book7.60x
Revenue growth+65.7%
Operating margin-92.7%
Net margin-89.1%
Return on equity-39.3%
Dividend yield—
Debt / equity0.24x

Results from SEC filings

Fiscal years, from Iovance Biotherapeutics's 10-K filings. The deep dive has 15+ years, quarters and every line.

Fiscal year20212022202320242025
Revenue——$1M$164M$264M
Net income-$342M-$396M-$444M-$372M-$391M
Free cash flow-$266M-$313M-$384M-$364M-$336M
EPS (diluted)-$2.23-$2.49-$1.89-$1.28-$1.09
Operating margin——-38735.0%-240.9%-153.1%

Where the revenue comes from

Revenue by products, fiscal 2025.

Amtagvi$220M83%
PROLEUKIN$43M17%

Superinvestors who own IOVA

From each investor's latest 13F filing (what a 13F shows). 2 of the investors we track hold it.

InvestorLast quarterValue% of portfolioQuarter
Cliff Asness
AQR Capital Management
Added $16M0.01%Q2 2026
Jay Petschek
Corsair Capital Management
Added $2M0.19%Q2 2026

Insider buying

Open-market purchases by Iovance Biotherapeutics's executives and directors in the last 12 months, from SEC Form 4 filings. What insider buying tells you.

No open-market insider purchases of IOVA in the last 12 months. Most insider activity is selling and option exercises, which aren't shown here.

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In the full deep dive

DCF fair value per share
Yearly return (IRR) at today's price
Growth implied by revenue and margins
15+ years of statements and quarters

Questions

Are Iovance Biotherapeutics insiders buying the stock?

No open-market insider purchases of IOVA in the last 12 months, according to SEC Form 4 filings.

Which superinvestors own Iovance Biotherapeutics?

2 of the superinvestors Investingly tracks hold IOVA in their latest 13F, including Cliff Asness, Jay Petschek.

Prices and ratios as of Oct 7, 2026; statements from SEC filings. Information only, not investment advice. Superinvestor holdings come from 13F filings, which are filed up to 45 days after each quarter ends.