Denali Therapeutics (DNLI)

$19.45 +4.18% on the day Market cap $3.1B 52-week range $13.75 to $27.30 Prices as of Oct 11, 2026

What the price implies

A reverse DCF: instead of guessing a fair value, it asks what growth today's price already assumes. How it works.

Denali Therapeutics's free cash flow was negative in fiscal 2025, so a cash-flow reverse DCF doesn't give a meaningful answer. The Modeling tab works from revenue and margins instead.

Fundamental grade

F

Five factors scored 1 to 9 from DNLI's latest numbers, weighted into one grade. It describes the business, not whether the stock is a buy.

Profitability0
Financial health8

Results from SEC filings

Fiscal years, from Denali Therapeutics's 10-K filings. Ten years of the full income statement, balance sheet and cash flow.

Fiscal year20212022202320242025
Revenue$49M$105M$331M$0$0
Net income-$291M-$326M-$145M-$423M-$513M
Free cash flow-$220M-$263M-$371M-$364M-$422M
EPS (diluted)-$2.39-$2.60-$1.06-$2.57-$2.97
Operating margin-607.8%-324.3%-59.5%——

Superinvestors who own DNLI

From each investor's latest 13F filing (what a 13F shows). 1 of the investors we track hold it.

InvestorLast quarterValue% of portfolioQuarter
Cliff Asness
AQR Capital Management
Added $10M0.00%Q2 2026

Insider buying

Open-market purchases by Denali Therapeutics's executives and directors in the last 12 months, from SEC Form 4 filings. What insider buying tells you.

No open-market insider purchases of DNLI in the last 12 months. Most insider activity is selling and option exercises, which aren't shown here.

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In the full deep dive

DCF fair value per share
Yearly return (IRR) at today's price
Growth implied by revenue and margins
15+ years of statements and quarters

Questions

Are Denali Therapeutics insiders buying the stock?

No open-market insider purchases of DNLI in the last 12 months, according to SEC Form 4 filings.

Which superinvestors own Denali Therapeutics?

1 of the superinvestors Investingly tracks hold DNLI in their latest 13F, including Cliff Asness.

Prices and ratios as of Oct 11, 2026; statements from SEC filings. Information only, not investment advice. Superinvestor holdings come from 13F filings, which are filed up to 45 days after each quarter ends.