Septerna (SEPN)
What the price implies
A reverse DCF: instead of guessing a fair value, it asks what growth today's price already assumes. How it works.
At a market value of $2.0B, Septerna's free cash flow of $110M (fiscal 2025) would need to grow about 4% a year for the stock to be worth today's price.
Assumes a 9% discount rate and 3% growth after year 10, on free cash flow (operating cash flow minus capital spending) from Septerna's SEC filings. Change any assumption, or model revenue and margins instead, in the Modeling tab, or try your own numbers in the reverse DCF calculator.
Fundamental grade
Five factors scored 1 to 9 from SEPN's latest numbers, weighted into one grade. It describes the business, not whether the stock is a buy.
Key numbers
Results from SEC filings
Fiscal years, from Septerna's 10-K filings. Ten years of the full income statement, balance sheet and cash flow.
| Fiscal year | 2023 | 2024 | 2025 |
|---|---|---|---|
| Revenue | $151,000 | $1M | $46M |
| Net income | $4M | -$72M | -$49M |
| Free cash flow | -$42M | -$70M | $110M |
| EPS (diluted) | $0.29 | -$7.26 | -$1.10 |
| Operating margin | 1374.2% | -7518.4% | -148.6% |
Superinvestors who own SEPN
From each investor's latest 13F filing (what a 13F shows). 3 of the investors we track hold it.
| Investor | Last quarter | Value | % of portfolio | Quarter |
|---|---|---|---|---|
| PRIMECAP Management PRIMECAP Management Co |
Added | $39M | 0.02% | Q2 2026 |
| Cliff Asness AQR Capital Management |
Added | $515,646 | 0.0% | Q2 2026 |
| Joel Greenblatt Gotham Asset Management |
New position | $312,194 | 0.00% | Q2 2026 |
Insider buying
Open-market purchases by Septerna's executives and directors in the last 12 months, from SEC Form 4 filings. What insider buying tells you.
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In the full deep dive
Questions
What growth does Septerna's stock price imply?
At a market value of $2.0B, Septerna would need its free cash flow to grow about 4% a year for 10 years (discounted at 9%, 3% growth after that) to be worth today's price.
Are Septerna insiders buying the stock?
No open-market insider purchases of SEPN in the last 12 months, according to SEC Form 4 filings.
Which superinvestors own Septerna?
3 of the superinvestors Investingly tracks hold SEPN in their latest 13F, including PRIMECAP Management, Cliff Asness, Joel Greenblatt.
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Prices and ratios as of Oct 11, 2026; statements from SEC filings. Information only, not investment advice. Superinvestor holdings come from 13F filings, which are filed up to 45 days after each quarter ends.