Septerna (SEPN) financial statements

Healthcare · Biotechnology · Market cap $2.0B

Septerna reported revenue of $46M in fiscal 2025, up 1644.5% a year over 2 years.

Net income was -$49M and the operating margin -148.6%, against 1374.2% in 2023.

Free cash flow was $110M.

The diluted share count rose 1933% over the period (dilution).

Revenue and free cash flow

Fiscal years, $ billions.

-0.1-0.100.10.10.1202320242025RevenueFree cash flow
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Income statement

Fiscal years, from Septerna's 10-K filings with the SEC.

Fiscal year202320242025
Revenue$151,000$1M$46M
Research and development$36M$65M$98M
Selling, general and admin$10M$17M$29M
Operating income$2M-$81M-$68M
Pre-tax income-$49M-$72M-$49M
Income tax$691,000-$498,000$12,000
Net income$4M-$72M-$49M
EPS (diluted)$0.29-$7.26-$1.10
Diluted shares2M10M44M
Operating margin1374.2%-7518.4%-148.6%
Net margin2768.2%-6678.9%-106.4%

Balance sheet

Fiscal years, from Septerna's 10-K filings with the SEC.

Fiscal year202320242025
Cash and short-term investments$88M$351M$391M
Receivables$151,000$171,000$10M
Total current assets$113M$357M$411M
Property, plant and equipment$5M$5M$4M
Total assets$131M$457M$596M
Total current liabilities$7M$13M$87M
Total liabilities$20M$37M$214M
Shareholders' equity-$38M$420M$382M
Net debt-$88M-$238M-$121M

Cash flow

Fiscal years, from Septerna's 10-K filings with the SEC.

Fiscal year202320242025
Operating cash flow-$39M-$67M$110M
Capital spending$3M$2M$518,000
Free cash flow-$42M-$70M$110M
Stock-based compensation$2M$3M$8M
Free cash flow margin-27550.3%-6471.9%238.7%
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Questions

What was Septerna's revenue in 2025?

$46M in fiscal 2025, from its 10-K filing.

How much free cash flow does Septerna generate?

$110M in fiscal 2025 (operating cash flow minus capital spending).

From Septerna's annual reports filed with the SEC (XBRL data), standardised by Investingly. Information only, not investment advice.