Ionis Pharmaceuticals (IONS) Superinvestor holders
19 of the superinvestors we track hold Ionis Pharmaceuticals (IONS) in their latest 13F filings, $1.0B in total.
Summary
The largest holder is Two Sigma (Two Sigma Investments), with $496M, 0.4% of the portfolio.
In their latest quarter: 1 opened a new position, 7 added, 11 trimmed.
Who holds it
Each investor's latest 13F filing, largest stake first. What a 13F shows.
| Investor | Last change | Shares | Value | % of portfolio | Filed for |
|---|---|---|---|---|---|
| Two Sigma Two Sigma Investments |
Added | 6,252,342 | $496M | 0.4% | Q2 2026 |
| Artisan Partners | Added | 2,640,024 | $209M | 0.3% | Q2 2026 |
| Tweedy, Browne Tweedy, Browne Company |
Trimmed | 1,793,400 | $80M | 6.5% | Q3 2026 |
| David Vogel Voloridge Investment Management |
Trimmed | 655,454 | $52M | 0.2% | Q2 2026 |
| Arrowstreet Capital | Trimmed | 632,028 | $50M | 0.0% | Q2 2026 |
| Jim Simons Renaissance Technologies |
Added | 559,414 | $44M | 0.1% | Q2 2026 |
| Cathie Wood ARK Investment Management |
Added | 300,770 | $24M | 0.2% | Q2 2026 |
| David Shaw D. E. Shaw & Co. |
Trimmed | 297,041 | $24M | 0.0% | Q2 2026 |
| Joel Greenblatt Gotham Asset Management |
Added | 121,252 | $10M | 0.0% | Q2 2026 |
| Ken Fisher Fisher Investments |
Added | 182,997 | $8M | 0.0% | Q3 2026 |
| Alger Fred Alger Management |
Added | 78,932 | $6M | 0.0% | Q2 2026 |
| Cliff Asness AQR Capital Management |
Trimmed | 22,059 | $2M | 0.0% | Q2 2026 |
| Ken Tropin Graham Capital Management |
New position | 16,717 | $1M | 0.1% | Q2 2026 |
| Ron Baron Baron Capital (BAMCO) |
Trimmed | 14,000 | $1M | 0.0% | Q2 2026 |
| Man Group Man Group plc |
Trimmed | 12,361 | $980,104 | 0.0% | Q2 2026 |
| Murray Stahl Horizon Kinetics LLC |
Trimmed | 10,904 | $864,578 | 0.0% | Q2 2026 |
| Ensign Peak Ensign Peak Advisors |
Trimmed | 9,120 | $723,125 | 0.0% | Q2 2026 |
| Paul Marshall Marshall Wace |
Trimmed | 8,501 | $674,044 | 0.0% | Q2 2026 |
| Fred DiSanto Ancora Holdings |
Trimmed | 2,215 | $175,627 | 0.0% | Q2 2026 |
Holders by quarter
| Quarter | Superinvestors holding it |
|---|---|
| Q2 2026 | 19 |
| Q1 2026 | 20 |
| Q4 2025 | 25 |
| Q3 2025 | 24 |
| Q2 2025 | 17 |
| Q1 2025 | 14 |
| Q4 2024 | 15 |
| Q3 2024 | 18 |
Questions about Ionis Pharmaceuticals
Which superinvestors own Ionis Pharmaceuticals?
19 of the superinvestors we track hold Ionis Pharmaceuticals (IONS) in their latest 13F filings, $1.0B in total. Two Sigma, Artisan Partners, Tweedy, Browne, David Vogel, Arrowstreet Capital, Jim Simons.
Who is the largest superinvestor holder of IONS?
The largest holder is Two Sigma (Two Sigma Investments), with $496M, 0.4% of the portfolio.
From Ionis Pharmaceuticals's annual reports filed with the SEC (XBRL data), standardised by Investingly. Information only, not investment advice.