The short version

From the latest prices and each company's SEC filings. Who's ahead on each measure, not which to buy.

  • Thermo Fisher Scientific is the larger company, worth $245.5B, about 4.3 times Natera.
  • Natera grew revenue faster over the last year (+37.7% vs +10.5%).
  • Thermo Fisher Scientific keeps more of each dollar of revenue as operating profit (17.6% vs -10.7%).
  • Natera's price assumes faster free cash flow growth: about 51% a year, against 14% for Thermo Fisher Scientific (reverse DCF).

Side by side

The stronger figure is shaded where higher (or, for valuation multiples, lower) reads as better. How the implied growth works.

MeasureNTRATMO
Market cap$57.6B$245.5B
Share price$400.71$658.02
Revenue (last fiscal year)$2.3B$44.6B
Free cash flow (last fiscal year)$109M$6.3B
Revenue growth, last year+37.7%+10.5%
Revenue growth per year, last 5 fiscal years+38.6%+3.2%
Operating margin-10.7%17.6%
Net margin-7.1%15.0%
Return on equity-10.6%13.2%
P/E (trailing)—36.3x
Price / free cash flow527.9x39.0x
EV / EBITDA—23.7x
FCF growth the price implies50.7%13.7%
Dividend yield—0.27%
Debt / equity0.46x1.15x
Fundamental gradeDC
Superinvestors holding it916
Insider purchases, last 12 months08

Results from SEC filings

Revenue and free cash flow by fiscal year, from each company's 10-K filings.

Natera

YearRevenueFree cash flowOp. margin
2021$625M-$376M-74.8%
2022$820M-$479M-66.0%
2023$1.1B-$286M-41.2%
2024$1.7B$69M-13.1%
2025$2.3B$109M-13.4%

Thermo Fisher Scientific

YearRevenueFree cash flowOp. margin
2021$39.2B$6.8B25.6%
2022$44.9B$6.9B18.7%
2023$42.9B$6.9B16.0%
2024$42.9B$7.3B17.1%
2025$44.6B$6.3B17.4%

Where the revenue comes from

Natera · by products, 2025

Product$2.3B100%
Licensing and other$10M0%

Thermo Fisher Scientific · by segments, 2025

Laboratory Products and Biopharma Services$23.8B53%
Life Sciences Solutions$8.8B20%
Analytical Instruments$7.4B17%
Specialty Diagnostics$4.6B10%
Compare them in fullFifteen years of statements, quarterly results, DCF and IRR models, and any number of peers side by side.
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Questions

Which is bigger, Natera or Thermo Fisher Scientific?

Thermo Fisher Scientific (TMO), at $245.5B against $57.6B.

Which grows faster, NTRA or TMO?

Natera: revenue grew +37.7% over the last year, against +10.5%.

Prices and ratios as of the last daily update; statements from SEC filings. Information only, not investment advice.