TEM vs TXG: Tempus AI and 10X Genomics compared
The short version
From the latest prices and each company's SEC filings. Who's ahead on each measure, not which to buy.
- Tempus AI is the larger company, worth $12.0B, close to 10X Genomics's $11.7B.
- Tempus AI grew revenue faster over the last year (+21.6% vs -12.7%).
- 10X Genomics keeps more of each dollar of revenue as operating profit (-14.3% vs -19.8%).
Side by side
The stronger figure is shaded where higher (or, for valuation multiples, lower) reads as better. How the implied growth works.
| Measure | TEM | TXG |
|---|---|---|
| Market cap | $12.0B | $11.7B |
| Share price | $70.35 | $80.65 |
| Revenue (last fiscal year) | $1.3B | $643M |
| Free cash flow (last fiscal year) | -$239M | $130M |
| Revenue growth, last year | +21.6% | -12.7% |
| Revenue growth per year, last 5 fiscal years | +58.3% | +7.0% |
| Operating margin | -19.8% | -14.3% |
| Net margin | -17.8% | -12.2% |
| Return on equity | -57.2% | -9.1% |
| P/E (trailing) | — | — |
| Price / free cash flow | — | 89.6x |
| EV / EBITDA | — | — |
| FCF growth the price implies | — | 24.9% |
| Dividend yield | — | — |
| Debt / equity | 4.32x | 0.25x |
| Fundamental grade | F | F |
| Superinvestors holding it | 3 | 3 |
| Insider purchases, last 12 months | 2 | 0 |
Results from SEC filings
Revenue and free cash flow by fiscal year, from each company's 10-K filings.
Tempus AI
| Year | Revenue | Free cash flow | Op. margin |
|---|---|---|---|
| 2022 | $321M | -$187M | -82.8% |
| 2023 | $532M | -$249M | -36.9% |
| 2024 | $693M | -$211M | -99.7% |
| 2025 | $1.3B | -$239M | -19.9% |
10X Genomics
| Year | Revenue | Free cash flow | Op. margin |
|---|---|---|---|
| 2021 | $490M | -$123M | -10.7% |
| 2022 | $516M | -$165M | -32.5% |
| 2023 | $619M | -$64M | -42.9% |
| 2024 | $611M | -$6M | -31.9% |
| 2025 | $643M | $130M | -9.5% |
Where the revenue comes from
Tempus AI · by products, 2025
Diagnostics$955M75%
Data and applications$316M25%
10X Genomics · by products, 2025
Products and services revenue$597M93%
License and royalty revenue$46M7%
Compare them in fullFifteen years of statements, quarterly results, DCF and IRR models, and any number of peers side by side.
Open TEM in InvestinglyQuestions
Which is bigger, Tempus AI or 10X Genomics?
Tempus AI (TEM), at $12.0B against $11.7B.
Which grows faster, TEM or TXG?
Tempus AI: revenue grew +21.6% over the last year, against -12.7%.
Prices and ratios as of the last daily update; statements from SEC filings. Information only, not investment advice.