AMGN vs AZN: Amgen and AstraZeneca compared
The short version
From the latest prices and each company's SEC filings. Who's ahead on each measure, not which to buy.
- AstraZeneca is the larger company, worth $238.8B, close to Amgen's $217.3B.
- Amgen grew revenue faster over the last year (+9.5% vs +8.6%).
- Amgen keeps more of each dollar of revenue as operating profit (30.0% vs 23.4%).
- On earnings, AstraZeneca is the cheaper stock (24.3x vs 28.0x).
- AstraZeneca's price assumes faster free cash flow growth: about 9% a year, against 9% for Amgen (reverse DCF).
Side by side
The stronger figure is shaded where higher (or, for valuation multiples, lower) reads as better. How the implied growth works.
| Measure | AMGN | AZN |
|---|---|---|
| Market cap | $217.3B | $238.8B |
| Share price | $414.87 | $159.20 |
| Revenue (last fiscal year) | $36.8B | $58.7B |
| Free cash flow (last fiscal year) | $8.1B | $8.7B |
| Revenue growth, last year | +9.5% | +8.6% |
| Revenue growth per year, last 5 fiscal years | +9.1% | +11.9% |
| Operating margin | 30.0% | 23.4% |
| Net margin | 22.9% | 17.4% |
| Return on equity | 74.8% | 22.9% |
| P/E (trailing) | 28.0x | 24.3x |
| Price / free cash flow | 26.8x | 20.3x |
| EV / EBITDA | 13.5x | 15.2x |
| FCF growth the price implies | 8.8% | 9.2% |
| Dividend yield | 2.3% | 2.0% |
| Debt / equity | 7.18x | 1.51x |
| Fundamental grade | B | C |
| Superinvestors holding it | 10 | 9 |
| Insider purchases, last 12 months | 8 | 1 |
Results from SEC filings
Revenue and free cash flow by fiscal year, from each company's 10-K filings.
Amgen
| Year | Revenue | Free cash flow | Op. margin |
|---|---|---|---|
| 2021 | $26.0B | $8.4B | 29.4% |
| 2022 | $26.3B | $8.8B | 36.3% |
| 2023 | $28.2B | $7.4B | 28.0% |
| 2024 | $33.4B | $10.4B | 21.7% |
| 2025 | $36.8B | $8.1B | 24.7% |
AstraZeneca
| Year | Revenue | Free cash flow | Op. margin |
|---|---|---|---|
| 2021 | $37.4B | $3.8B | 2.8% |
| 2022 | $44.4B | $7.2B | 8.5% |
| 2023 | $45.8B | $6.6B | 17.9% |
| 2024 | $54.1B | $7.3B | 18.5% |
| 2025 | $58.7B | $8.7B | 23.4% |
Where the revenue comes from
Amgen · by products, 2025
Product sales$35.1B96%
Other revenues$1.6B4%
AstraZeneca · by products, 2021
Tagrisso$5.0B14%
Vaxzevria$3.9B11%
Farxiga$3.0B8%
Symbicort$2.7B7%
Imfinzi$2.4B7%
Lynparza$2.3B6%
Compare them in fullFifteen years of statements, quarterly results, DCF and IRR models, and any number of peers side by side.
Open AMGN in InvestinglyQuestions
Which is bigger, Amgen or AstraZeneca?
AstraZeneca (AZN), at $238.8B against $217.3B.
Is AMGN or AZN cheaper?
By trailing P/E, AstraZeneca (24.3x) is cheaper than Amgen (28.0x). A lower multiple can also mean the market expects less growth.
Which grows faster, AMGN or AZN?
Amgen: revenue grew +9.5% over the last year, against +8.6%.
Prices and ratios as of the last daily update; statements from SEC filings. Information only, not investment advice.